TLDR
The National Science Foundation (NSF) awards approximately $9 billion annually to advance fundamental research and STEM education. Although the dominant NSF funding pathway is universities and research institutions, nonprofit organizations - particularly informal science education organizations (museums, science centers, public media, after-school networks), STEM-focused community-based organizations, and research-affiliated nonprofits - are eligible applicants for many NSF programs. Nonprofit-relevant programs include Advancing Informal STEM Learning (AISL), Discovery Research PreK-12 (DRK-12), Innovative Technology Experiences for Students and Teachers (ITEST), INCLUDES, Research Experiences for Teachers (RET), Research Coordination Networks, and several Education and Human Resources directorate programs. NSF awards are governed by 2 CFR Part 200 (Uniform Guidance), 2 CFR Part 2500 (NSF supplement), and the NSF Proposal & Award Policies & Procedures Guide (PAPPG). Applications are submitted through Research.gov; post-award management uses Research.gov plus the Award Cash Management $ervice (ACM$). The most distinctive NSF compliance requirements are responsible conduct of research (RCR) training, biographical sketch and current and pending support requirements, the data management and sharing plan, and indirect cost rate negotiation through NSF's Cost Analysis and Audit Resolution (CAAR) Branch.
The National Science Foundation is best known as a research funder for universities, but its Directorate for STEM Education and several research-adjacent programs make NSF a regular and meaningful funder for science museums, public media organizations, after-school STEM networks, science-engagement nonprofits, and research-affiliated nonprofits. NSF’s compliance environment is distinctive - fewer prescriptive program requirements than most federal grantmakers but more rigorous proposal preparation requirements through PAPPG, and a research-integrity framework (responsible conduct of research training, data management and sharing plan, conflict of interest) that is unusual for nonprofits accustomed to social-services federal grantmaking.
What NSF funds
NSF funds basic research and STEM education across all major directorates. Nonprofit-eligible programs cluster in the Directorate for STEM Education (formerly Education and Human Resources) plus several research-related programs across other directorates.
Advancing Informal STEM Learning (AISL). AISL funds research and innovation in informal STEM learning - projects led by museums, science centers, planetariums, zoos and aquariums, public media organizations, after-school programs, citizen science initiatives, libraries, and community-based organizations. AISL has six funding tracks (Pilots and Feasibility Studies; Research in Service to Practice; Innovations in Development; Broad Implementation; Conferences; Literature Reviews/Syntheses) with budgets ranging from $300,000 for small studies to $5 million for broad implementation projects.
Discovery Research PreK-12 (DRK-12). DRK-12 funds research and development on STEM education in PreK-12 settings, including curriculum development, teacher professional development, and learning assessments. Projects typically run three to five years with budgets from $450,000 (capacity building) to $5 million (development and implementation studies).
Innovative Technology Experiences for Students and Teachers (ITEST). ITEST funds projects that engage K-12 students in STEM technology experiences. Strategy, Developing and Testing Innovations, and Successful Project Expansion strands accommodate projects at different scales.
INCLUDES. The Inclusion across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science initiative funds networks broadening participation in STEM. Design and Development Launch Pilots and Alliances are the primary funding mechanisms.
Research Experiences for Teachers (RET). RET funds nonprofit-led research experiences for K-12 STEM teachers, supplements to existing NSF research awards, and stand-alone Sites.
Research Coordination Networks (RCN). RCN funds nonprofit-hosted research coordination across distributed researchers and organizations.
Innovation Corps (I-Corps). I-Corps Hubs and Sites support entrepreneurship and commercialization training for researchers; some Hub awards are nonprofit-eligible.
Public Engagement with Science. Various directorates fund public engagement, science communication, and informal learning supplements.
Workforce development. Programs supporting graduate and postdoctoral training intersect with nonprofit research training organizations.
Application requirements
NSF proposals are submitted through Research.gov.
Prerequisites. Active SAM.gov registration with valid UEI; Research.gov organizational and individual user accounts; a current NSF-approved indirect cost rate (negotiated with NSF’s Cost Analysis and Audit Resolution Branch if NSF is your cognizant federal agency, or honored from your existing NICRA if another agency is cognizant).
Proposal package. PAPPG-required sections include Cover Sheet, Project Summary (with Overview, Intellectual Merit, and Broader Impacts sections), Project Description (typically 15 pages), References Cited, Biographical Sketches (using the SciENcv-generated NSF format), Budget and Budget Justification, Current and Pending (Other) Support, Facilities Equipment and Other Resources, Data Management and Sharing Plan, Mentoring Plan (if postdocs are budgeted), and program-specific attachments. NSF proposals that fail to comply with PAPPG formatting requirements (font, margins, page limits) are returned without review.
Intellectual Merit and Broader Impacts. NSF’s two merit review criteria. Both must be addressed in the Project Summary and Project Description. Reviewers explicitly score on both criteria. Broader Impacts addresses the project’s potential to benefit society and contribute to specific desired societal outcomes; for nonprofit informal STEM applicants this often centers on access, equity, and community engagement.
Responsible Conduct of Research (RCR). Institutions submitting NSF proposals must certify that they have a plan to provide RCR training to undergraduate students, graduate students, and postdoctoral researchers supported by NSF funds. The plan must be documented and implemented before training begins.
Conflict of interest. Institutions must maintain written conflict-of-interest policies covering financial conflicts of interest of investigators, with disclosure mechanisms and management plans for identified conflicts.
Post-award setup. Awards are issued through Research.gov. Drawdowns flow through the Award Cash Management $ervice (ACM$). Awardees report expenditures through ACM$ rather than submitting SF-425 reports separately.
Compliance specifics
NSF awards are governed by 2 CFR Part 200, 2 CFR Part 2500 (NSF supplement), and the NSF PAPPG.
Cost principles. The five Uniform Guidance criteria apply. NSF-specific cost considerations include the prohibition on entertainment and alcohol, restrictions on participant support costs (generally not subject to indirect costs and tracked separately), and conditions on equipment and capital expenditures.
Procurement. 2 CFR 200 Subpart D applies. NSF awardees often have lower transaction volumes than other federal recipients but the same procurement standards apply.
Time-and-effort documentation. Standard 2 CFR 200.430(i) records-of-effort requirements apply. NSF awardees with academic-style appointments must address summer salary, academic-year salary, and effort certifications.
Data Management and Sharing. NSF requires a Data Management and Sharing Plan in every proposal, describing how the project will manage and share research data. Awardees must implement the approved plan and address data sharing in the Final Project Report.
Reporting cadence. Annual Project Reports are due 90 days before the end of each project year, submitted through Research.gov. The Final Project Report and Project Outcomes Report are due 120 days after the project end date. Financial expenditure data is reported continuously through ACM$.
Single Audit. Nonprofits expending $1,000,000 or more in federal awards in a fiscal year must obtain a Single Audit under 2 CFR 200 Subpart F. NSF participates in the cooperative audit resolution process and follows up on findings affecting NSF awards.
Subrecipient monitoring. NSF awardees that subaward portions of their awards become passthrough entities under 2 CFR 200.332. The risk assessment, subaward agreement content, and ongoing monitoring requirements apply.
Indirect cost rate. If NSF is your cognizant federal agency, your indirect cost rate is negotiated through NSF’s Cost Analysis and Audit Resolution (CAAR) Branch. If another federal agency is your cognizant agency, NSF honors your existing NICRA.
Research integrity. NSF awardees must comply with research misconduct policy at 45 CFR Part 689, RCR training requirements, and conflict-of-interest policy at 2 CFR 200.318. Findings of research misconduct are referred to the NSF Office of Inspector General.
Human and animal subjects. Awards involving human subjects research require IRB approval and Federalwide Assurance with the HHS Office for Human Research Protections. Awards involving vertebrate animal research require Institutional Animal Care and Use Committee approval.
Deadlines and solicitation cadence
NSF program solicitations have program-specific submission cycles:
- AISL - typically annual deadline in early winter.
- DRK-12 - typically annual deadline in fall or early winter.
- ITEST - typically annual deadline in summer.
- INCLUDES - episodic; specific program tracks have specific deadlines.
- RET - Sites typically annual; supplements rolling.
- RCN - biannual deadlines.
- Most disciplinary research programs - twice-annual proposal windows or no deadline (rolling submission with target dates).
The NSF program solicitation page lists current and upcoming opportunities. Subscribe to the NSF Funding Opportunities email updates to receive solicitation announcements. NSF proposals typically have longer preparation cycles than most federal grant applications because of the depth of the Project Description and the time needed to coordinate biographical sketches, current and pending support, and budget justification across all senior personnel.
Common mistakes
Five recurring failure modes for first-time NSF nonprofit recipients:
- PAPPG formatting noncompliance. Proposals returned without review for font, margin, page limit, or section heading violations. PAPPG compliance is the gating issue before substantive review.
- Weak Broader Impacts section. A Project Description that addresses Intellectual Merit but treats Broader Impacts as an afterthought scores poorly even with strong technical content.
- Indirect cost rate confusion. Nonprofits without a NICRA and without confirmed eligibility for the 10% de minimis rate face budget rejections.
- Late annual Project Reports. Project Reports submitted late delay continuation funding decisions and can affect future proposal competitiveness.
- Data Management and Sharing Plan implementation gaps. A DMSP that was approved at proposal but not implemented at the project surfaces in Final Project Report review.
Where to go next
Read the practical guide to 2 CFR Part 200 for the cost principles framework that governs every NSF award. Review federal grant reporting requirements before your first Project Report. The cognizant agency for indirect costs guide explains how cognizant-agency assignment affects your NSF indirect cost rate negotiation. The Subpart E cost principles guide walks through the cost-by-cost framework NSF cost analysts apply during budget review. The free grant compliance checklist walks through the documentation set NSF recipients should maintain through closeout.
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- PAPPG
- The NSF Proposal & Award Policies & Procedures Guide. NSF's authoritative reference for proposal preparation, submission, review, award, and administration. Updated periodically; the version in effect at proposal submission is the operative one.
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- Research.gov
- NSF's grants management system for proposal preparation and submission, project reporting, and post-award administration. Has largely replaced FastLane for new submissions.
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- Award Cash Management $ervice (ACM$)
- NSF's payment system through which grantees draw down federal funds. Award expenditure data submitted through ACM$ replaces the SF-425 submission requirement for most NSF awards.
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